In the nucleus, the DNA twin helix is packaged by one-of-a-kind proteins (histones) to form a complicated called chromatin. The dyed undergoes additional condensation to form the chromosome. So while the dyed is a lower order that DNA organization, chromosomes are the greater order of DNA organization. One organism’s genetic content is count in terms of the chromosome pairs present. E.g. Humans have 23 pairs of chromosomes.

You are watching: The major structural difference between chromatin and chromosomes is that the latter are

Comparison chart

dyed versus Chromosome comparison chart
ChromatinChromosomeDefinition Structure Appearance Pairs Metabolic activity Presence Conformation Visualization
In the nucleus, the DNA dual helix is packaged by distinct proteins (histones) to type a complicated called chromatin. The chromatin undergoes further condensation to form the chromosome. A compact framework of nucleic acids and protein discovered in the cell nucleus of most living cells, carrying hereditary information in the form of genes.
Composed that nucleosomes-a facility of DNA and proteins (called histones). Stand for DNA folded on nucleoproteins by a size of 50. The dyed fiber is app. 10 nm in diameter. Chromosomes space condensed dyed Fibers. They space a higher order that DNA organization, where DNA is condensed at the very least by 10,000 times onto itself.
Chromatin Fibers space Long and also thin. They space uncoiled structures found inside the nucleus. Chromosomes space compact, thick and also ribbon-like. These are coiled frameworks seen prominently throughout cell division.
Chromatin is unpaired. Chromosome is paired.
Permissive come DNA replication, RNA synthetic (transcription) and also recombination events. Refractory to this processes.
Found transparent the cabinet cycle. Distinctly visible during cell department (metaphase, anaphase) as highly condensed frameworks upto several thousand nm.
May have actually open (euchromatin) or compact (heterochromatin) conformations, i beg your pardon is dynamically regulated during the cell-cycle stages. Predominantly heterochromatic state v a predetermined place in the nucleus and also a details shape such together metacentric, submetacentric, acrocentric, telocentric.
Electron microscopic lense (beads on wire appearance) Light microscopic lense (classic four-arm structure when duplicated)

Structure and also Formation

The structural reality of chromatin is the nucleosome — a complex of DNA and histones. A dyed fiber is roughly 10 nm in diameter. Chromatins stand for DNA urgently on nucleoproteins through a magnitude of 50.

Chromosomes are created of compacted chromatin where DNA is condensed at least by 10,000 time onto itself.


The significant structures in DNA compaction; DNA, the nucleosome, the 10nm "beads-on-a-string" fibre (chromatin), 30nm fibre (chromatin), and also the metaphase chromosomes. Click come enlarge.

While chromatin is permissive come DNA replication, RNA synthetic (transcription), and recombination events, the chromosomes space refractory come these processes as they room tightly coiled.


Chromatin is found in all stages the the cabinet cycle and also they undergo additional coiling to form chromosomes that space distinctly visible during cell department as very condensed frameworks (upto several thousand nm). Depending upon the number of chromosomes, a cell may be diploid or haploid.


Chromatin is visible in a cabinet via one electron microscopic lense where it reflects the typical beads on string appearance.

Chromosomes space much much easier to visualize and can be seen making use of a irradiate microscope.

See more: Difference Between Class And Individual Evidence, Module 06 :: Class And Individual Characteristics


Chromatin has either open (euchromatin) or compact (heterochromatin) conformations, which is dynamically regulated during the cell-cycle stages. Chromosomes have actually a primarily heterochromatic state with a predetermined position in the nucleus and a details shape such together metacentric, submetacentric, acrocentric or telocentric.