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How a lot food is vital to act as a buffer to safeguard the stomach?
Some doctors insurance claim that a pair of crackers are enough, whereas various other medical professionals claim that you have to eat an entire meal.
So what"s the truth? And what are the best foods items to eat (or drink) for this purpose?
In order to simplify your answer, feel cost-free to answer for an "average" adult, meaning average weight, height, and so on, and also no particular illnesses that would complicate your answer.
(As a side note, not all pills have to be taken with food; some pills are to be taken on an empty stomach.)
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As you mentioned in the side note, it really counts on the kind of pill. Because there are chemical interactions between the food and also the pill e.g. tetracycline and milk (tetracycline and also calcium create complexes, for this reason inactivating the antibiotic).
Generally the gastric pH is not so crucial for the drug uptake, as it happens in the tiny intestine. However some drugs have the right to acquire damaged in acid, therefore some pills have an acid resistant coating. This coat is usually a weak acid. Since the gastric pH is very low (1-3) weak acids remain protonated, for this reason are not polar and can not be addressed in water. Later in the duodenum the pH varies between 8-9, the coating weak acid deprotonates and dissolves. The drug is collection cost-free. This is the reason why you can"t split all pills!
The reason why you must eat some food with some medicaments is that they can irritate your gastric lining (e.g. diclofenac) and also food serves as a buffer as it "dilutes" the medicament. Other substances need the food to function appropriately e.g. iron requirements to be taken through orange juice or various other vitamin c rich juices (the gastric acid oxidays Fe2+ -> Fe3+, but Fe3+ cannot be absorbed, therefore vitamin c is needed as a reduction agent).
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The question which food is the ideal can"t really be answered as each patient is various. As long as the food does not damage the medication any kind of food you like is great. Normally some crackers are sufficient, but if you begin to feel stomach pain, eating more would certainly be a great principle. Because a lot of medicaments need to be taken at a addressed time of the day, taking them 5 minutes after a continual meal is a good idea.
However some food should not be eaten while taking medication because they induce/inhilittle the cytochrome P450 system in the liver and therefore resulting in insufficent or dangerous high blood levels of the medicapoint out.